The purposes of this research were to: 1) develop an entrepreneurship course in the occupation area for secondary 6 students, 2) compare the learning achievement before and after learning this course, 3) compare the practical skills before and after learning the palm-leaf hat weaving unit, and 4) study students’ satisfaction with the entrepreneurship course. The sample used in this research was a group of 38 secondary 6/2 students who were studying in the first semester of the academic year 2023 from Trattrakarnkhun School, gained from purposive sampling. The research instruments included: 1) a form to assess the school course outline, 2) lesson plans for the selective course in the occupation subject area, 3) a 30-item learning achievement test, 4) a 10-item palm-leaf hat weaving practical skill test based on three-level-criterion-referenced assessment (Rubrics), and 5) a form to survey students’ satisfaction towards this course. The statistics used for data analysis included: mean, standard deviation and t-test.